Player Draft
| Name | State | School | Class | Pos. | Year | Round | Team |
| Nick Potter | MO | Lee's Summit West | 2022 | RHP | 2025 | 5 | Houston Astros |
| Caden Powell | OK | Clinton | 2022 | SS | 2024 | 6 | Astros |
| Ryan Powers | IL | Nazareth | 2011 | RHP | 2014 | 22 | Phillies |
| Ryan Prager | TX | Hillcrest | 2021 | LHP | 2025 | 9 | Clevelan Guardians |
| Anthony Prato | NY | Poly Prep Country Day | 2016 | SS | 2019 | 7 | Twins |
| Cooper Pratt | MS | Magnolia Heights | 2023 | SS | 2023 | 6 | Brewers |
| Christian Pregent | FL | Atlantic | 2019 | C | 2023 | 10 | Mets |
| Peyton Prescott | FL | TNXL Academy | 2023 | RHP | 2025 | 5 | New York Mets |
| Jared Price | PA | Twin Valley | 2012 | RHP | 2017 | 37 | Marlins |
| Collin Price | GA | Lambert | 2018 | C | 2022 | 6 | Astros |
| Patrick Pridgen | MN | Apple Valley | 2017 | RHP | 2022 | 15 | Tigers |
| Connor Prielipp | WI | Tomah | 2019 | LHP | 2022 | 2 | Twins |
| Quinn Priester | IL | Cary Grove | 2019 | RHP | 2019 | 1 | Pirates |
| William Privette | SC | Chapin | 2020 | RHP | 2023 | 13 | Rangers |
| James Proctor | MO | MICDS | 2016 | RHP | 2020 | UDFA | Reds |
| Owen Proksch | TX | Southlake Carroll | 2021 | - | 2025 | 9 | Texas Rangers |
| Michael Prosecky | IL | Nazareth | 2019 | LHP | 2022 | 6 | Rockies |
| Jacob Pruitt | IN | Yorktown | 2022 | RHP | 2025 | 15 | Philadelphia Phillies |
| Drew Puglielli | FL | Gulf Coast | 2016 | 3B | 2016 | 40 | White Sox |
| Owen Puk | IA | Marion | 2021 | RHP | 2025 | 18 | Washington Nationals |
| Keegan Pulford-Thorpe | ON | Newmarket | 2019 | LHP | 2019 | 33 | San Diego Padres |
| Cal Quantrill | ON | Port Hope | 2013 | RHP | 2016 | 1 | Padres |
| Dylan Questad | WI | Waterford | 2023 | RHP | 2023 | 5 | Twins |
| Riley Quick | AL | Hewitt Trussville | 2022 | RHP | 2025 | CB-A | Minnesota Twins |
| Braden Quinn | CT | New Fairfield | 2021 | LHP | 2024 | 14 | Diamondbacks |
| JT Quinn | FL | Berkeley Prep | 2022 | RHP | 2025 | CB-B | Baltimore Orioles |
| James Quinn-Irons | VA | South Lakes High | 2022 | OF | 2025 | 5 | Tampa Bay Rays |
| Zachary Raabe | MN | Forest Lake | 2018 | 2B | 2021 | 8th | Minnesota Twins |
| Kendall Radcliffe | IL | Morgan Park | 2010 | OF | 2010 | 25 | Rangers |
| Danny Rafferty | IL | Loyola | 2013 | OF | 2016 | 35 | Athletics |
| Cole Ragans | FL | North Florida Christian | 2016 | LHP | 2016 | 1 | Rangers |
| Josiah Ragsdale | NJ | St. Augustine Prep | 2022 | OF | 2025 | 7 | Milwaukee Brewers |
| Bryce Rainer | CA | Harvard Westlake | 2024 | SS | 2024 | 1 | Tigers |
| Max Rajcic | CA | Orange Lutheran | 2020 | RHP | 2022 | 6 | Cardinals |
| Lucas Raley | OH | Highland | 2013 | OF | 2016 | 7 | Dodgers |
| Blake Rambusch | TX | Gateway College Prep | 2018 | SS | 2022 | 15 | Mariners |
| Rafael Ramirez | FL | Calusa Prep | 2015 | RHP | 2015 | 33 | Giants |
| Luis Ramirez | CA | Bishop Mora Salesian | 2019 | RHP | 2022 | 7 | Rangers |
| Lucas Ramirez | FL | American Heritage Plantation | 2024 | OF | 2024 | 17 | Angels |
| Javier Ramos | OK | Vian | 2018 | RHP | 2022 | 18 | Rockies |
| Alex Ramos | NY | Goshen | 2024 | RHP | 2024 | UDFA | Baltimore Orioles |
| Ryan Ramsey | NJ | Pascack Hills | 2019 | LHP | 2022 | 13 | Royals |
| Garrett Ramsey | MS | Northwest Rankin | 2018 | RHP | 2022 | 16 | Red Sox |
| Caleb Ramsey | GA | Heritage (Conyers) | 2018 | OF | 2018 | 25th | Red Sox |
| Josh Randall | CA | Capistrano Valley Christian | 2021 | C | 2024 | 3 | Tigers |
| Alexander Rao | FL | Oxbridge Academy | 2018 | RHP | 2022 | 8 | Phillies |
| Shawn Rapp | NJ | Delbarton | 2019 | LHP | 2022 | 20 | Guardians |
| Nick Raquet | PA | State College | 2014 | LHP | 2017 | 3 | Nationals |
| Tyler Ras | NJ | Middletown North | 2018 | RHP | 2018 | 33 | Chicago Cubs |
| Connor Rasmussen | SC | Fort Mill | 2022 | SS | 2025 | 15 | Kansas City Royals |
| Carter Rasmussen | TX | Northwest | 2022 | RHP | 2025 | 14 | Boston Red Sox |
| Eric Rataczak | MN | Totino-Grace | 2019 | - | 2024 | 16 | Marlins |
| John Rave | IL | Bloomington Central Catholic | 2016 | OF | 2019 | 5 | Royals |
| Andy Ravel | PA | Wilson | 2013 | RHP | 2016 | 7 | Blue Jays |
| Corey Ray | IL | Simeon | 2013 | OF | 2016 | 1 | Brewers |
| Anthony Ray | IL | St. Rita | 2013 | OF | 2013 | 36 | Cardinals |
| Johnny Ray | IL | Quincy Notre Dame | 2017 | RHP | 2021 | 12 | Chicago White Sox |
| Dylan Ray | AL | Bob Jones | 2020 | RHP | 2022 | 4 | Diamondbacks |
| Cole Raymond | CT | Avon Old Farms | 2025 | RHP | 2025 | 17 | Los Angeles Angels |
| Chris Razo | IL | Illinois Valley Central | 2009 | RHP | 2013 | 24 | Brewers |
| Joseph Redfield | TX | Midway | 2020 | OF | 2023 | 4 | Angels |
| Zachary Redner | FL | Strawberry Crest | 2023 | RHP | 2024 | 20 | Angels |
| A.J. Reed | IN | Terre Haute South | 2011 | LHP | 2014 | 2 | Astros |
| Carlson Reed | GA | Marietta | 2020 | RHP | 2023 | 4 | Pirates |
| Ryan Reed | PA | The Haverford School | 2022 | LHP | 2025 | 15 | San Diego Padres |
| Canon Reeder | OR | Summit | 2022 | OF | 2025 | 18 | Pittsburgh Pirates |
| Simon Reid | CA | Palos Verdes | 2019 | C | 2022 | 10 | Dodgers |
| Rocco Reid | SC | Greenville | 2021 | LHP | 2024 | 15 | Diamondbacks |
| Dominick Reid | TX | Frisco Lone Star | 2022 | RHP | 2025 | 3 | Chicago Cubs |
| Evan Reifert | IA | Wilton | 2017 | RHP | 2018 | 30 | Texas Rangers |
| Kevin Reiher | IL | Eisenhower | 2013 | C | 2014 | 24 | Braves |
| James Reilly | NY | Albertus Magnus | 2016 | RHP | 2016 | 38 | Mariners |
| Patrick Reilly | NJ | Christian Brothers Academy | 2020 | RHP | 2023 | 5 | Pirates |
| Jacob Reimer | CA | Yucaipa | 2022 | 3B | 2022 | 4 | Mets |
| Jason Reitz | CA | Pioneer | 2022 | RHP | 2025 | 4 | Minnesota Twins |
| Zach Reks | IL | Sandburg | 2012 | 3B | 2017 | 10 | Dodgers |
| Jacob Remily | HI | Maryknoll | 2024 | 3B | 2024 | 16 | Guardians |
| Chase Renner | PA | Brandywine Heights | 2021 | RHP | 2025 | 13 | Miami Marlins |
| Heath Renz | WI | Jefferson | 2014 | RHP | 2018 | 27 | Rays |
| Tyler Renz | NY | Fox Lane | 2024 | RHP | 2024 | 18 | Brewers |
| Sean Renzi | IL | Plainfield North | 2011 | RHP | 2016 | 32 | White Sox |
| Cameron Repetti | CA | Cypress | 2019 | 3B | 2019 | 36th | Giants |
| Adam Retzbach | PA | Lakeland | 2019 | C | 2022 | 14 | Orioles |
| Grant Reuss | MI | Cranbrook Kingswood | 2014 | LHP | 2017 | 29 | Tigers |
| Carlos Rey | FL | Miami Springs Senior | 2020 | LHP | 2023 | 17 | Diamondbacks |
| Daniel Reyes | FL | Mater Academy Charter | 2015 | OF | 2015 | 39 | Red Sox |
| Mark Reyes | AR | Jessieville | 2011 | LHP | 2011 | 46 | Orioles |
| Ryan Reynolds | LA | Ouachita Christian | 2016 | 3B | 2019 | 14th | Cubs |
| Eric Reyzelman | CA | De La Salle | 2019 | RHP | 2022 | 5 | Yankees |
| Dylan Rheault | IL | Glenbard South | 2010 | RHP | 2013 | 19 | Orioles |
| Jeremy Rhoades | IL | Wheaton Warrenville South | 2011 | RHP | 2014 | 4 | Angels |
| David Rhodes | BC | Langley Fine Arts | 2018 | RHP | 2018 | 40 | Seattle Mariners |
| Caleb Ricca | LA | Dutchtown High School | 2016 | SS | 2019 | 23rd | Mariners |
| Ben Rice | MA | Noble and Greenough | 2018 | C | 2021 | 12 | New York Yankees |
| Owen Rice | WI | East Troy | 2021 | LHP | 2024 | 20 | Cardinals |
| Jordan Rich | FL | American Heritage (Plantation) | 2025 | OF | 2025 | 17 | Toronto Blue Jays |
| Lyon Richardson | FL | Jensen Beach | 2018 | RHP | 2018 | 2 | Reds |
| Grant Richardson | IN | Fishers | 2018 | OF | 2021 | 17 | Yankees |
| Tre Richardson | TX | Kingwood | 2020 | SS | 2023 | 15 | Cardinals |
| Grant Richardson | AZ | Horizon | 2022 | LHP | 2025 | 6 | Athletics |