Player Draft
| Name | State | School | Class | Pos. | Year | Round | Team |
| Wallace Clark | OK | Holland Hall | 2021 | SS | 2025 | 9 | Arizona Diamondbacks |
| Chris Clark | PA | The Haverford School | 2020 | RHP | 2023 | 5 | Angels |
| Logun Clark | CA | Taft | 2022 | C | 2022 | 16 | Guardians |
| Kinkade Clark | MS | Brandon | 2023 | 3B | 2025 | 15 | Baltimore Orioles |
| Wesley Clarke | VA | Liberty Christian | 2018 | C | 2018 | 40 | Brewers |
| Denzel Clarke | ON | Everest Academy | 2018 | OF | 2021 | 4 | Oakland Athletics |
| Brandon Clarke | VA | Independence | 2021 | LHP | 2024 | 5 | Red Sox |
| Wesley Clarke | VA | Marshall | 2021 | RHP | 2021 | 10 | Brewers |
| Seth Clausen | IA | Pleasant Valley | 2021 | RHP | 2025 | 16 | Colorado Rockies |
| Cutter Clawson | CA | Laguna Beach | 2019 | LHP | 2019 | 33rd | Nationals |
| Logan Clayton | FL | New Smyrna Beach | 2018 | RHP | 2022 | 17 | Diamondbacks |
| Cameron Clayton | OR | Lakeridge | 2021 | SS | 2024 | 14 | Marlins |
| Jake Clemente | FL | Stoneman Douglas | 2022 | RHP | 2025 | 7 | Miami Marlins |
| Alex Clemmey | RI | Bishop Hendricken | 2023 | LHP | 2023 | 2 | Guardians |
| Matthew Cleveland | CT | Windsor | 2016 | RHP | 2016 | 12 | Mets |
| Tyler Cleveland | AR | Sheridan | 2018 | RHP | 2022 | 14 | Mariners |
| Nolan Clifford | IL | Neuqua Valley | 2020 | SS | 2024 | 17 | Rockies |
| Ryan Clifford | NC | Pro5 Academy | 2022 | OF | 2022 | 11 | Astros |
| Patrick Clohisy | MO | Chaminade | 2020 | OF | 2024 | 11 | Braves |
| Corbin (CJ) Clouse | MI | Grand Ledge | 2013 | OF | 2016 | 27 | Braves |
| Kyle Cody | WI | McDonell Central | 2012 | RHP | 2016 | 6 | Rangers |
| Micah Coffey | IL | Batavia | 2014 | 3B | 2018 | 30 | White Sox |
| Adisyn Coffey | IN | Delta | 2017 | SS | 2020 | 3 | White Sox |
| Cutter Coffey | CA | Liberty | 2022 | SS | 2022 | 2 | BOS |
| Spence Coffman | MS | Tishomingo County | 2022 | SS | 2022 | 19 | Padres |
| Justin Cohen | FL | Riverview | 2015 | C | 2015 | 6 | Marlins |
| Trevor Cohen | NJ | Holy Spirit | 2022 | OF | 2025 | 3 | San Francisco Giants |
| Parker Coil | OK | Edmond Memorial | 2022 | LHP | 2025 | 16 | Milwaukee Brewers |
| Dazon Cole | MI | West Bloomfield | 2014 | SS | 2014 | 29 | Braves |
| Ethan Cole | WI | Winnebago Lutheran Academy | 2022 | LHP | 2025 | 20 | Colorado Rockies |
| Zach Cole | MO | Springfield Catholic | 2019 | - | 2022 | 10 | Astros |
| Ronell Coleman | IL | Simeon | 2013 | SS | 2017 | 34 | Tigers |
| Dylan Coleman | MO | Potosi | 2015 | RHP | 2018 | 4 | Padres |
| Javen Coleman | TX | Home School | 2020 | LHP | 2023 | 16 | Dodgers |
| Dennis Colleran | MA | North Attleboro | 2021 | RHP | 2024 | 7 | Royals |
| TJ Collett | IN | Terre Haute North Vigo | 2016 | 1B | 2016 | 40 | Twins |
| Keshun Collier | MS | Mendenhall | 2020 | OF | 2022 | 20 | Cubs |
| Cam Collier | GA | Mount Paran | 2022 | 3B | 2022 | 1 | Reds |
| Isaac Collins | MN | Maple Grove | 2016 | 2B | 2019 | 9 | Rockies |
| Corey Collins | GA | North Gwinnett | 2020 | C | 2024 | 6 | Mets |
| Gavin Collyer | GA | Mountain View | 2019 | RHP | 2019 | 12 | Texas Rangers |
| Edgar Colon | FL | Varela | 2024 | RHP | 2024 | 11 | Reds |
| Dalton Combs | IN | Adams Central | 2013 | OF | 2017 | 35 | Giants |
| Aaron Combs | FL | IMG Academy | 2020 | RHP | 2024 | 8 | White Sox |
| Chris Comito | IA | Norwalk | 2015 | RHP | 2015 | 15 | White Sox |
| Brandon Compton | AZ | Buckeye Union | 2022 | LHP | 2025 | 2 | Miami Marlins |
| Charlie Condon | GA | The Walker School | 2021 | 1B | 2024 | 1 | Rockies |
| Griffin Conine | FL | Pine Crest | 2015 | OF | 2015 | 31 | Marlins |
| Cal Conley | OH | West Clermont | 2018 | SS | 2021 | 4 | Atlanta Braves |
| Shane Conlon | IL | Naperville Central | 2010 | LHP | 2013 | 21 | Royals |
| Jack Conlon | TX | Clements | 2017 | RHP | 2017 | 4th | Baltimore |
| Cole Conn | IL | St. Charles East | 2020 | C | 2023 | 12 | Athletics |
| Justin Connell | FL | American Heritage | 2017 | SS | 2017 | 11 | Nationals |
| Charlie Connolly | PA | Radnor | 2017 | RHP | 2021 | 20 | Dodgers |
| Shane Connolly | NC | Pine Lake Preparatory | 2017 | RHP | 2021 | 10 | Royals |
| Caden Connor | CA | Orange Lutheran | 2019 | OF | 2023 | 19 | White Sox |
| Drew Conover | NJ | Voorhees | 2020 | RHP | 2022 | 20 | Tigers |
| Ethan Conrad | NY | Saugerties | 2022 | 1B | 2025 | 1 | Chicago Cubs |
| Nicholas Conte | RI | North Providence | 2020 | RHP | 2024 | 8 | Royals |
| Nick Conti | FL | Dr Phillips | 2015 | 2B | 2015 | 40 | Mets |
| Gavin Conticello | FL | Stoneman Douglas | 2021 | SS | 2021 | 8 | Arizona Diamondbacks |
| Austin Conway | IN | Delta | 2013 | RHP | 2018 | 31 | White Sox |
| Sean Cook | MD | Walt Whitman | 2016 | RHP | 2016 | 40 | Nationals |
| Casey Cook | VA | Freedom (South Riding) | 2021 | OF | 2024 | 3 | Rangers |
| Alex Cook | GA | Apalachee | 2019 | RHP | 2022 | 12 | Rays |
| Jake Cook | MS | Madison Central | 2022 | LHP | 2025 | 3 | Toronto Blue Jays |
| Sam Coonrod | IL | Carrollton | 2011 | RHP | 2014 | 5 | Giants |
| Shane Cooper | MO | Timberland | 2013 | 2B | 2017 | 37 | Tigers |
| Tanner Cooper | NY | Canandaigua Academy | 2017 | RHP | 2019 | 35th | Cincinatti Reds |
| Riley Cooper | CA | Clovis North | 2020 | LHP | 2023 | 13 | Orioles |
| Everett Cooper | NC | Pro5 Academy | 2022 | SS | 2022 | 16 | Nationals |
| Patrick Copen | WV | Parkersburg Catholic | 2020 | RHP | 2023 | 7 | Dodgers |
| Pierce Coppola | NJ | Verona | 2021 | LHP | 2025 | 7 | Chicago Cubs |
| Kaleb Corbett | KY | Fern Creek | 2020 | RHP | 2024 | 20 | Rays |
| Billy Corcoran | PA | Malvern Prep | 2018 | RHP | 2018 | 36 | Rangers |
| Matthew Corlew | FL | North Broward Prep | 2019 | OF | 2019 | 23rd | Los Angeles Angels |
| Brayden Corn | NC | North Henderson | 2022 | OF | 2025 | 15 | Seattle Mariners |
| Riley Cornelio | CO | Pine Creek | 2019 | RHP | 2022 | 7 | Nationals |
| Chris Cornelius | MO | St. John Vianney | 2016 | SS | 2019 | 16 | Phillies |
| Octavio Corona | CA | Otay Ranch | 2019 | RHP | 2019 | 39th | Blue Jays |
| Carlos Cortes | FL | Lake Howell | 2016 | OF | 2016 | 20 | Mets |
| Chris Cortez | NV | Silverado | 2021 | RHP | 2024 | 2 | Angels |
| Harold Cortijo | MD | Riverdale Baptist | 2017 | RHP | 2017 | 14 | Yankees |
| Andrew Cossetti | PA | La Salle | 2018 | C | 2022 | 11 | Twins |
| Mike Costanzo | IL | St. Rita | 2014 | LHP | 2018 | 31 | Rays |
| Jack Costello | CA | Chaminade Prep | 2020 | 3B | 2024 | 10 | Padres |
| Marty Costes | MD | Archbishop Curley | 2015 | OF | 2017 | 25 | Astros |
| Magdiel Cotto | SC | Nation Ford | 2020 | LHP | 2023 | 11 | Pirates |
| Quin Cotton | CO | Regis Jesuit | 2016 | OF | 2016 | 38 | Rockies |
| Paul Coumoulos | FL | College of Central Florida | 2017 | OF | 2017 | 40 | Phillies |
| Brady Counsell | WI | Whitefish Bay | 2021 | SS | 2025 | 10 | Arizona Diamondbacks |
| Isaiah Coupet | IL | Homewood-Flossmoor | 2020 | LHP | 2023 | 4 | Rockies |
| Corey Cousin | LA | Slidell High School | 2024 | OF | 2024 | 18 | Royals |
| Jake Cousins | IL | Wheaton | 2013 | RHP | 2017 | 20 | Nationals |
| Benjamin Cowles | NY | Newark | 2018 | SS | 2021 | 10 | New York Yankees |
| Jonah Cox | CO | Broomfield | 2020 | OF | 2023 | 6 | Athletics |
| Jackson Cox | WA | Toutle Lake | 2022 | RHP | 2022 | 2 | Rockies |
| Brenner Cox | TX | Prosper Rock Hill | 2022 | OF | 2022 | 4 | Nationals |
| Jacob Cozart | NC | Wesleyan Christian | 2021 | C | 2024 | 2 | Guardians |
| Dylan Craig | IL | Murphysboro | 2011 | LHP | 2014 | 12 | Rockies |