Player Draft
| Name | State | School | Class | Pos. | Year | Round | Team |
| Hiro Wyatt | CT | Staples | 2023 | RHP | 2023 | 3 | Royals |
| Hayden Wynja | IN | Heritage Christian | 2017 | LHP | 2017 | 30 | Braves |
| Blaine Wynk | OH | Miamisburg | 2022 | RHP | 2025 | 8 | Chicago White Sox |
| Jack Yalowitz | IL | Loyola | 2015 | OF | 2019 | 10 | Rockies |
| Nien-Hsi Yang 陽念希 | TW | University of Taipei | 2024 | RHP | 2024 | San Francisco Giants | |
| Tyler Yankosky | PA | Wyoming Valley West | 2016 | RHP | 2019 | 19 | Nationals |
| Nick Yarnall | PA | Hempfield | 2013 | 1B | 2016 | 35 | Dodgers |
| Mike YaSenka | PA | Franklin Area | 2016 | RHP | 2019 | 17 | Cardinals |
| Evan Yates | CA | Martin Luther King | 2021 | RHP | 2024 | 20 | Orioles |
| Justin Yeager | IL | Plainfield North | 2016 | RHP | 2019 | 33 | Braves |
| Chay Yeager | GA | Starr's Mill | 2021 | SS | 2023 | 12 | Toronto Blue Jays |
| Colin Yeaman | CA | Saugus High | 2022 | SS | 2025 | 4 | Baltimore Orioles |
| Andy Yerzy | ON | York Mills Collegiate | 2016 | C | 2016 | 2 | Diamondbacks |
| Trey Yesavage | PA | Boyertown | 2021 | RHP | 2024 | 1 | Blue Jays |
| Craig Yoho | IN | Fishers | 2018 | SS | 2023 | 8 | Brewers |
| Nick Yorke | CA | Archbishop Mitty | 2020 | SS | 2020 | 1 | Boston |
| Eric Yost | NY | Fordham Prep | 2020 | RHP | 2023 | 17 | Padres |
| Jordan Yost | FL | Sickles High School | 2025 | SS | 2025 | 1 | Detroit Tigers |
| Alex Young | IL | Carmel Catholic | 2012 | LHP | 2015 | 2 | Diamondbacks |
| Kyle Young | NY | St. Dominic | 2016 | LHP | 2016 | 22 | Phillies |
| Taylor Young | LA | West Monroe | 2017 | SS | 2022 | 8 | Dodgers |
| Jared Young | MN | Bemidji | 2017 | OF | 2017 | 15 | Cubs |
| Carter Young | WA | Selah | 2019 | SS | 2022 | 17 | Orioles |
| Jack Young | IA | Pleasant Valley | 2020 | RHP | 2024 | 9 | White Sox |
| Cole Young | PA | North Allegheny | 2022 | SS | 2022 | 1 | Mariners |
| Ethan Young | NC | Hickory Ridge | 2022 | RHP | 2025 | 5 | St. Louis Cardinals |
| Quentin Young | CA | Oaks Christian | 2025 | SS | 2025 | 2 | Minnesota Twins |
| Luke Young | TX | San Angelo | 2020 | RHP | 2022 | 11 | Nationals |
| Ike Young | IL | Monticello | 2025 | SS | 2025 | 20 | Tampa Bay Rays |
| Trent Youngblood | KY | Trinity | 2020 | 2B | 2024 | 10 | 314 |
| Sean Youngerman | CA | Chaminade College Preparatory | 2022 | RHP | 2025 | 4 | Philadelphia Phillies |
| Cole Zaffiro | NY | Manhasset | 2020 | RHP | 2024 | UDFA | New York Yankees |
| Nick Zammarelli | RI | Lincoln Senior | 2013 | 3B | 2016 | 8 | Mariners |
| Nazzan Zanetello | MO | Christian Brothers College | 2023 | SS | 2023 | 2 | Red Sox |
| Angel Zarate | NC | Rockingham County | 2017 | OF | 2022 | 17 | Guardians |
| Jacob Zebron | MD | Colonel Richardson | 2018 | RHP | 2018 | 18th | Orioles |
| Adam Zebrowski | NY | Christian Brothers Academy | 2018 | C | 2021 | 13 | Atlanta Braves |
| Garrett Zech | FL | Naples | 2015 | OF | 2015 | 15 | Dodgers |
| Ryan Zeferjahn | KS | Seaman | 2016 | RHP | 2019 | 3 | Red Sox |
| TJ Zeuch | OH | Mason | 2013 | RHP | 2016 | 1 | Blue Jays |
| Jacob Zibin | BC | Langley | 2023 | RHP | 2022 | 10 | Guardians |
| Malique Ziegler | IA | Des Moines East | 2014 | OF | 2016 | 22 | Giants |
| Calvin Ziegler | ON | TNXL Academy | 2021 | RHP | 2021 | 2 | New York Mets |
| Gage Ziehl | NY | Penfield | 2021 | RHP | 2024 | 4 | Yankees |
| Zane Zielinski | IL | Lake View | 2020 | SS | 2024 | 9 | Giants |
| Michael Zimmerman | FL | Gulf Coast | 2015 | LHP | 2015 | 11 | Rockies |
| Keegan Zinn | FL | Lake Minneola | 2023 | RHP | 2023 | 12 | Guardians |
| Jake Zitella | IL | St. Charles East | 2023 | 3B | 2023 | 16 | Mets |
| Steven Zobac | CA | Valley Christian | 2019 | RHP | 2022 | 4 | Royals |
| Nick Zona | VA | Hanover | 2018 | RHP | 2022 | 20 | Mariners |
| Donovan Zsak | NJ | St. Joseph's Metuchen | 2022 | LHP | 2024 | 8 | Guardians |
| Nick Zwack | MN | Monticello | 2017 | LHP | 2021 | 17th | NY Mets |
| Tony Zych | IL | St. Rita | 2008 | RHP | 2011 | 4 | Cubs |